Shirou Itagaki Selected Research

Embryonal Rhabdomyosarcoma

1/2012	[Effects of acidification and alkalinization agents on statins-induced muscle toxicity].
1/2011	AMP-activated protein kinase regulates the expression of monocarboxylate transporter 4 in skeletal muscle.
4/2008	Association between risk of myopathy and cholesterol-lowering effect: a comparison of all statins.
1/2007	Effect of medium pH on the cytotoxicity of hydrophilic statins.
7/2005	Transport mechanism for L-lactic acid in human myocytes using human prototypic embryonal rhabdomyosarcoma cell line (RD cells).

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Shirou Itagaki Research Topics

Disease

10	Ischemia 01/2012 - 08/2006
5	Embryonal Rhabdomyosarcoma 01/2012 - 07/2005
5	Breast Neoplasms (Breast Cancer) 11/2009 - 05/2005
3	Reperfusion Injury 01/2011 - 08/2006
3	Hepatolenticular Degeneration (Wilson's Disease) 12/2007 - 04/2004
2	Rhabdomyosarcoma 05/2012 - 07/2005
2	Muscular Diseases (Myopathy) 04/2008 - 08/2007
1	Respiratory Tract Diseases (Respiratory Tract Disease) 10/2016
1	Ventricular Tachycardia 01/2013
1	Hypoxia (Hypoxemia) 05/2012
1	Neoplasms (Cancer) 01/2012
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2012
1	Diarrhea 11/2009
1	Hepatocellular Carcinoma (Hepatoma) 04/2008
1	Multiple Myeloma 03/2008
1	Choriocarcinoma 02/2008
1	Myotoxicity 08/2007
1	Cardiac Arrhythmias (Arrythmia) 08/2007
1	Wounds and Injuries (Trauma) 08/2006

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2012 - 05/2005
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2012 - 08/2007
3	AntioxidantsIBA 08/2011 - 11/2006
3	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2011 - 01/2006
3	Multidrug Resistance-Associated Protein 2IBA 11/2009 - 01/2006
3	Irinotecan (Camptosar)FDA LinkGeneric 11/2009 - 05/2005
2	Amiodarone (Amiodarona)FDA LinkGeneric 01/2013 - 08/2007
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2012 - 07/2005
2	LuteinIBA 08/2011 - 08/2006
2	Multidrug Resistance-Associated ProteinsIBA 06/2008 - 08/2007
2	CholesterolIBA 04/2008 - 08/2007
1	AerosolsIBA 10/2016
1	Liposomes (Liposome)IBA 10/2016
1	Protein Kinase CIBA 05/2012
1	Small Interfering RNA (siRNA)IBA 05/2012
1	Pregnane X ReceptorIBA 01/2012
1	Constitutive Androstane ReceptorIBA 01/2012
1	AcidsIBA 01/2012
1	DNA (Deoxyribonucleic Acid)IBA 01/2012
1	Indicators and Reagents (Reagents)IBA 01/2012
1	RNA (Ribonucleic Acid)IBA 01/2012
1	RotenoneIBA 01/2012
1	Uric Acid (Urate)IBA 01/2012
1	Citric Acid (Citrate)FDA LinkGeneric 01/2012
1	AICA ribonucleotide (ZMP)IBA 01/2011
1	caffeic acidIBA 01/2011
1	AMP-Activated Protein KinasesIBA 01/2011
1	Chlorogenic AcidIBA 01/2011
1	GenisteinIBA 01/2011
1	IsoflavonesIBA 01/2011
1	Digoxin (Digitek)FDA LinkGeneric 01/2010
1	XenobioticsIBA 11/2009
1	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2008
1	Adenosine Triphosphate (ATP)IBA 05/2008
1	pitavastatin (itavastatin)FDA Link 04/2008
1	Thalidomide (Thalomid)FDA Link 03/2008
1	Folic Acid (Vitamin M)FDA LinkGeneric 02/2008
1	CopperIBA 12/2007
1	Bicarbonates (Hydrogen Carbonate)IBA 08/2007
1	Rosuvastatin Calcium (Crestor)FDA Link 01/2007
1	Pravastatin (Pravachol)FDA LinkGeneric 01/2007
1	Free RadicalsIBA 08/2006
1	LactonesIBA 01/2006
1	Mitoxantrone (Novantrone)FDA LinkGeneric 05/2005
1	Phenolsulfonphthalein (Phenol Red)IBA 07/2004
1	Organic Anion TransportersIBA 07/2004
1	AnionsIBA 04/2004

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 01/2012
1	Intravenous Administration 01/2010
1	Chelation Therapy (Therapy, Chelation) 12/2007